CD Copy - Free download and software reviews. Prosnone cannot test the write CD function. Conscannot say, able to read but not to test the write. Summary. I downloaded a free trial to test it as it was mentionned and I was able to read a cd but when the time come to write, the scam. You have to buy it to write the CD. All of these kind of programs are potential scam, a real free trial is a time trial were you can test the complete procedure. Instead I downloaded a copy of free basic NERO and it worked perfectly. Reply to this review. Was this review helpful?(0) (0) Summaryagain, look at the options and be sure to tell the program what you want it to do. The interface has not changed much since V1. I know maybe you might think that because i'm a advanced user that I know how it works and all. Well check just look in the options and it that simple. Put in the Disk and the tracks show up, then you press . ![]() Free virtual CD ROM for Windows 2.1 driver download. All the latest manufacturer's drivers available for free from Software Patch. Extensive database updated.Easy CD DVD Copy is a tool to copy your CD or DVD collection. Easy CD DVD Copy is easy to use with neat interface without any complicated parameter settings. How to Copy or Burn a CD Using Windows Media Player. This wikiHow teaches you how to use Windows Media Player to copy, or "rip," a CD and then burn a new one. Time Limits : USB Copy Protection allows drive owners to optionally restrict accessto content in drive by setting expiry date. The program will check both local. As a technology enthusiast, I often get asked how to quickly burn or copy CDs, DVDs, or Blu-ray discs for free. Most people have heard of software like Rox. 53403 views What is the easiest way to copy CDs onto a USB using windows 7.
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Canon Announcements. From Canon USA. MELVILLE, N. Y., February 1. 4, 2. Developed and designed to meet the varying needs of entry- level and advanced amateur photographers, Canon U. ![]() S. A., Inc., a leader in digital imaging solutions, today announced two new additions to the celebrated EOS system – the EOS Rebel T7i DSLR camera, which adds to the popular Rebel series of entry- level DSLR cameras, and the EOS 7. D DLSR camera, which represents a new category of cameras for advanced amateur photographers. Canon also introduced today the new EF- S 1. IS STM lens and Wireless Remote Control BR- E1, as well as added functionality for the Canon Connect Station CS1. Suing people isn’t easy. Suing the President of the United States of America, however, is huge pain in the ass. But that hasn’t stopped a group of Twitter users. This is the World's BEST green screen software. It runs as a Photoshop plugin and creates a non-destructive layer system with unmatched spill suppression. You have not yet voted on this site! If you have already visited the site, please help us classify the good from the bad by voting on this site. The-Digital-Picture.com is your complete source for Canon Announcements. Detailed review of the Canon Pixma Pro-1, a 12 ink A3+ (13 inch width) printer for colour and black and white printing. ![]() Mobile toplist for mobile web sites. We have over 2000 registered sites. If you would like to show your support, you can always buy me a Coffee These listings are delib. In live view mode, both cameras utilize Canon’s Dual Pixel CMOS AF to deliver the world’s fastest AF focusing speed of 0. This technical achievement allows users to find their subject, focus accurately, and capture the shot more quickly than ever before. Both models also have built- in Wi- Fi, NFC and Bluetooth technology for easy transfer of images. It is also the first in the series with Dual Pixel CMOS AF with Phase- detection and the first with a DIGIC 7 Image Processor. Creative filters for both still images and video will allow users to customize the look and feel of their content in new and imaginative ways. Users will now be able to see on- screen how switching modes on the mode dial or tweaking settings can alter the image they are about to capture, guiding photographers on their way to capturing more compelling images, such as ones with a shallower depth- of- field or being able to give moving- subjects a frozen or flowing look. The EOS 7. 7D represents a new category of advanced amateur EOS cameras, a step above the Rebel series. Users of the EOS 7. D DSLR camera will benefit from features like the 7. RGB+IR Metering Sensor, similar to the one found in the EOS 8. D camera and Anti- Flicker shooting mode to help combat the on- and- off repetitive flickering from artificial lights found in high- school gyms or auditoriums. The EOS 7. 7D also features a top LCD panel and quick control dial for photographers who desire quicker and easier access to changing and controlling settings on the camera. Features of the lens include. Compact- size, Standard Zoom Lens with High Image Quality. Lead Screw- type STMImage Stabilization at up to 4 Stops of Shake Correction. Stylish Design. The Canon EF- S 1. IS STM lens is scheduled to be available in early April 2. This new remote allows photographers to capture images from within a 1. This camera accessory is useful for photographers who are looking to capture images remotely in situations where there could be issues with signal reception or line- of- sight to the camera. The Canon Wireless Remote Control BR- E1 will be compatible with both the EOS Rebel T7i and EOS 7. D cameras. The Canon BR- E1 is schedule to be available in April 2. Canon is also announcing today a firmware update to the Canon Connect Station CS1. The firmware update includes the following improvements. Compatibility for select Canon and non- Canon cameras, with a wider range of supported file formats. Support for video playback of computer- edited movies. Improved smartphone connectivity and compatibility. For more information about the Canon Connect Station firmware update, please visit usa. For photographers who demand premium performance, the new EOS M6 Camera features the company’s 2. Megapixel APS- C CMOS image sensor able to capture sharp, high- resolution images even in low- light situations, its most advanced image processor, DIGIC 7, and super- fast Dual Pixel CMOS AF speed, enabling photographers to capture clear, sharp, high- resolution images and Full HD videos. Additional advanced EOS camera technologies built into the EOS M6 camera include. Fast & Accurate Dual Pixel CMOS AF with Phase- detection. Megapixel CMOS (APS- C) Sensor. High- speed Continuous Shooting at up to 7. AF Lock)DIGIC 7 Image Processor, ISO 1. Full HD 6. 0p. Combination IS with five- axis Image Stabilization. Built- in Wi- Fi, NFC and Bluetooth technology. Intuitive Touch Screen, 3. Tilt- type LCDControl & Customize with Five Functional Dials. Compatible with EF, EF- S and EF- M Lenses & select EOS System Accessories. The Canon EOS M6 features an in- camera five- axis digital image stabilization to help reduce camera shake when shooting videos. When shooting with a compatible lens featuring IS the EOS M6 will leverage both the optical IS in the lens as well as the in- camera digital IS through a Combination IS system, to help deliver tremendously smooth videos. The three- inch touch screen tilts approximately 1. It will also be sold as part of body- and- lens kits with EF- M 1. F3. 5- 6. 3 IS STM zoom kit lens with an estimated retail price of $8. EF- M 1. 8- 1. 50mm f/3. IS STM lens for an estimated retail price of $1,2. April 2. 01. 7. For more information please visit, usa. Connectivity is very important to today’s photographers and the EOS M6 delivers built- in Wi- Fi, NFC and Bluetooth capability that can maintain a smooth constant connection with compatible smartphones or tablets when using the Canon Camera Connect App. Canon is also announcing today a firmware update to the Canon Connect Station CS1. The firmware update includes the following improvements. Compatibility for select Canon and non- Canon cameras, with a wider range of supported file formats. Support for video playback of computer- edited movies. Improved smartphone connectivity and compatibility. For more information about the Canon Connect Station firmware update, please visit usa. Version history - PTGui Stitching Software. Version 1. 0. 0. 1. February 2. 01. 7)Fix: After installing nvidia GPU driver 3. Windows PTGui would output corrupted jpg images. Fix: Batch Builder now sorts images with file names containing numbers in natural order (i. GPU acceleration for nvidia GPUs was disabled in PTGui 1. OS 1. 0. 1. 1 (El Capitan)dcraw has been updated to version 9. Version 1. 0. 0. 1. January 2. 01. 6)This updates reverts the change in PTGui 1. PTGui can now use more than 2 GB GPU memory on AMD cards under Windows'. It turned out this was causing problems on. AMD GPU drivers, resulting in empty images being created. If you have an AMD card with more than 2 GB RAM please see FAQ Q7. Version 1. 0. 0. 1. January 2. 01. 6)Fix: A bug was introduced in PTGui 1. With this update PTGui will use the decimal separator as configured in the operating system (as was the case prior to v. PTGui can now use more than 2 GB GPU memory on AMD cards under Windows. Previously this required setting an environment variable. For NVIDIA cards using more than 2. GB was already supported. Version 1. 0. 0. 1. October 2. 01. 5)GPU accelerated stitching no longer works under OS X 1. El Capitan) on NVIDIA GPUs. Unfortunately we have not been able to fix this yet as it appears to be caused by driver bugs in OS X. Until the issue is fixed PTGui by default now disables GPU acceleration on affected machines. It's possible to override this in Preferences - Advanced. Note that GPU acceleration with AMD GPUs is not affected, and NVIDIA cards under Windows work fine. A custom dcraw executable can be configured in Options / Preferences - Plugins. Fix: Mac: tool bar icons would be garbled on some Macs running OS X 1. Fix: Mac: Help button in the Panorama Editor window would open the wrong help page. Fix: . cr. 2 images could be loaded in the wrong orientation. This cause the batch stitcher to abort stitching with . Please reload the project and stitch again. This fixes a problem causing certain Nikon NEF files to have a low contrast. Fix: PTGui web viewer: intermittent freezing in Safari on OS 1. This is solved by having the viewer now using Web. GL on Safari when available. Fix: Mac: The Return key on a keyboard with numeric keypad would insert a newline in a text field. Now it behaves the same as the Enter key, causing the default (usually OK) button of a window to be pressed. Version 1. 0. 0. 1. December 2. 01. 4)Fix: Loading certain . This is actually a Firefox problem with CSS 3. D. To work around the problem the viewer now prefers to use Web. GL in Firefox (if available). The Batch Stitcher can now handle projects for which the pixel format of one or more source images has been changed after the project file was saved. Previously the batch stitcher would abort with an error if, for example, an alpha channel was added to an image after the project was saved. Version 1. 0. 0. 1. November 2. 01. 4)Fix: a bug was introduced in PTGui 1. CPU stitching to be slower than in previous versions. This is fixed now. Fix: crash when stitching certain projects. Fix: crash when aborting a stitch with . Version 1. 0. 0. 9 (4 November 2. Fix: crash or Assertion Failed error for certain projects. Version 1. 0. 0. 8 (3. October 2. 01. 4)Fix: for certain projects a vertical line could be seen at the - 1. Fix: for certain projects 'vortex artifacts' could be seen at the zenith when doing exposure fusion or tone mapping Fix: error 'Assertion failed . Tone mapping quality in general is improved. A Compression slider has been added. And there's a new Saturation slider to control the vibrancy of the colors. Fix: Using Viewpoint Correction for all images could result in a blurry panorama. Fix: Running the Batch Builder on folders containing raw images caused PTGui to crash. Fix: Mac: Error during installation: 'PTGui Pro can't be opened because the identity of the developer cannot be confirmed.'Version 1. September 2. 01. 4)Fix: GPU stitching was slow on Windows 7 with certain NVIDIA cards. Fix: PTGui could crash upon startup with certain outdated buggy GPU drivers. This can be overridden as always in Options - Advanced. The 6. 4 bit version is not affected. Fix: error 'CL. PTGui is limited to using 2. GB of GPU memory on this machine. The default blending feather (for new projects) is now sharper, to reduce problems with ghosting. This can be customized as always by moving the slider in the Create Panorama tab. Fix: RAW images in portrait format were loaded incorrectly. For an overview see What's new in PTGui 1. A new blazing fast, GPU accelerated stitching engine. Up to 1. 0 times faster stitching! PTGui now comes with a standalone viewer (Windows and Mac) for equirectangular panoramas. The viewer can also be used outside of PTGui. It supports full screen display on Windows and mac. On mac the trackpad can be used for navigation (swipe and pinch). The viewer can be launched through Tools - PTGui Viewer and via the View / Preview functions in PTGui. New tone mapping algorithm for HDR panoramas with very natural looking results (Pro version)The tone mapper (PTGui Pro only) can now be used for LDR panoramas as well. This works great for boosting the shadows in a non- bracketed panorama and can (at low ISO) avoid the need to shoot bracketed images. New menu Images - Select: this allows for example to delete all images outside the visible area of the panorama. Or. in conjunction with the yellow crop lines in the panorama editor, to delete images any rectangular area of the panorama. Options/Preferences - Advanced: RAM usage is now specified as an absolute number of megabytes; previously this was set as. RAMFaster loading of uncompressed tiff images from spinning hard disks (reduced chance of disk thrashing)HDR/Exposure tab: section 'HDR' has been reworded. Windows: The installer now adds PTGui to the 'Send To' context menu in Explorer. In Explorer you can select a set of images to be stitched, right click and choose 'Send to - > PTGui'.'Set optimum size' button now directly picks the optimum size (formerly 'maximum size' in the popup menu). The options 'For print' and 'For web' have been removed. Changes in the way external viewers are configured: In Options/Preferences - Advanced now up to 3 applications can be configured. These applications will be shown in the popup list under the View button (Create Panorama tab) and Preview button (Preview tab). The new PTGui Viewer is always included for equirectangular panoramas. PTGui now checks upon startup whether the configured temporary folders exist and can be written to; it will warn if there is a problem. Slightly improved detail in exposure fused result in areas with saturated colors. Updated dcraw to version 9. Added EXIF sensor size data for a number of cameras. Fix: mac: several windows had a keyboard shortcut Cmd+C for the Close or Cancel button. This would override the keyboard shortcut for copying to clipboard. These windows can now be closed using the Esc key and copying can be done using Cmd+C. Fix: mac: if individual lens settings were used, PTGui would crash if the lens type for an image was changed in the Image Parameters tab. Fix: Minor layout issues in main window. Fix: Blending artifacts when stitching RAW images. Fix: Blending artifacts when generating HDR panoramas. Fix: PTGui web viewer will no longer use CSS3. D in Firefox under Linux, due to rendering bugs in this browser. Fix: PTGui web viewer previously had a minimum size of approximately 3. Removed support for 1. HDR output: previously PTGui Pro could save HDR output in a 1. TIFF or PSD file. Note that this was a rarely used feature. PTStitcher is no longer supported. The 'Use Quicktime Player' option for previewing has been removed (current Quick. Time versions do not support panoramas anymore)Version 9. May 2. 01. 4)Fix: crash if a corrupt jpeg file was loaded. Fix: memory leak when loading a file with corrupt EXIF data. Fix: possible crash when a source image is modified externally. Fix: sorting images (Sort button in the Source Images tab) could take a very long time Fix: after optimization some control points could have a reported optimization distance of 0, while the actual error is very large. Fix: some settings saved by File - Make Default would be ignored if checkboxes in Project Settings - Template behaviour were unchecked. Fix: Numerical Transform window would show rounded values even if this was disabled in Options/Preferences. Fix: edges of the panorama were cut off for 3. Fix: Metadata window: certain GPS coordinates would be shown as e. Previously alphabetic ordering was used so '2. Added EXIF sensor size data for a number of cameras. PTGui Web Viewer: Fix: In some browsers autorotating would stop after a while. Fix: In some browsers, if pan or tilt limits were set (partial panorama) the display would be corrupted or the viewer would stop responding. Fix: mouse wheel zooming did not work in Firefox. Fix: mouse wheel zooming would also scroll the web page in which the viewer was embedded. If minimum and maximum pan bounds are set, autorotation no longer stops at the edge but reverses direction. Right mouse click popup window: the text in this window has been changed from 'Created with PTGui' to 'PTGui Viewer version x. On a mac the panorama can now be navigated by swiping with two fingers on the touchpad, or by swiping with one finger on the surface of the magic mouse. This can be disabled by adding 'enablemactouchpad: false' to the viewer options in the html source. Dragging while holding down the right mouse button now also zooms in and out. When autorotation starts the viewer will navigate towards the horizon. This is still the default but this behaviour can be disabled by adding 'autorotatetohorizon: false' to the viewer options in the html source. Version 9. 1. 9 (1. December 2. 01. 3)Panoramas can now be geotagged directly in PTGui: click the Metadata button in the Create Panorama tab to enter a GPS location and orientation. Together with the new geotagging feature this makes it. Google Plus, Google Views and Google Maps. You can even create. Microsoft Windows is a registered trademarks of Microsoft Corporation. Microsoft Corporation in no way endorses or is affiliated with windows. ![]() EMCO MSI Package Builder allows you to create MSI packages using an easy approach. Convert EXE to MSI and build packages for unattended installation. Automatically Update PC Drivers with Easy Driver Pro Access to 15,000,000 device drivers including 2,500,00 drivers that are specific to computer manufacturers such. A library of over 200,000 free and free-to-try applications and updates for Windows. 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Song of Myself. Won't you help support Day. Poems? 1. 81. 9- 1. I celebrate myself, and sing myself. And what I assume you shall assume. For every atom belonging to me as good belongs to you. I do not know what it is any more than he. I do not laugh at your oaths nor jeer you; ). The President holding a cabinet council is surrounded by the great. On the piazza walk three matrons stately and friendly with twined arms. The crew of the fish- smack pack repeated layers of halibut in the hold. The Missourian crosses the plains toting his wares and his cattle. As the fare- collector goes through the train he gives notice by the. The floor- men are laying the floor, the tinners are tinning the. In single file each shouldering his hod pass onward the laborers. Seasons pursuing each other the indescribable crowd is gather'd, it. Seventh- month, (what salutes of cannon and small arms!). Seasons pursuing each other the plougher ploughs, the mower mows. Off on the lakes the pike- fisher watches and waits by the hole in. The stumps stand thick round the clearing, the squatter strikes deep. Flatboatmen make fast towards dusk near the cotton- wood or pecan- trees. Coon- seekers go through the regions of the Red river or through. Tennessee, or through those of the Arkansas. Torches shine in the dark that hangs on the Chattahooche or Altamahaw. Patriarchs sit at supper with sons and grandsons and great- grandsons. In walls of adobie, in canvas tents, rest hunters and trappers after. The city sleeps and the country sleeps. The living sleep for their time, the dead sleep for their time. The old husband sleeps by his wife and the young husband sleeps by his wife. And these tend inward to me, and I tend outward to them. And such as it is to be of these more or less I am. And of these one and all I weave the song of myself. I resign myself to you also- -I guess what you mean. I behold from the beach your crooked fingers. I believe you refuse to go back without feeling of me. We must have a turn together, I undress, hurry me out of sight of the land. Cushion me soft, rock me in billowy drowse. Dash me with amorous wet, I can repay you. I will accept nothing which all cannot have their. I am possess'd! Iowa, Oregon, California? O welcome, ineffable grace of dying days! I plead for my brothers and sisters. Comment on Day. Poems? If you are like us, you have strong feelings about poetry, and about each poem you read. Let it all out! Comment on this poem, any poem, Day. Poems, other poetry places or the art of poetry at Day. Poems Feedback. Won't you help support Day. Poems? Click here to learn more about how you can keep Day. Poems on the Web . All rights reserved. The authors of poetry and other material appearing on Day. Poems retain full rights to their work. Any requests for publication in other venues must be negotiated separately with the authors. The editor of Day. Poems will gladly assist in putting interested parties in contact with the authors. Monograph: Coenzyme Q10 Help on accessing alternative formats, such as Portable Document Format (PDF), Microsoft Word and PowerPoint (PPT) files.Penreco offers a unique line of Petrolatums, Waxes, White Mineral Oils, and Gelled Hydrocarbons (Versagel® and Synergel® products) which are used in various. DESCRIPTION (See chart below for quantitative information.) Potassium Chloride in Dextrose and Sodium Chloride Injections USP are sterile, nonpyrogenic and contain no. DESCRIPTION. Estradiol valerate injection, USP contains estradiol valerate, a long-acting estrogen in sterile oil solutions for intramuscular use. Monograph: Caffeine Help on accessing alternative formats, such as Portable Document Format (PDF), Microsoft Word and PowerPoint (PPT) files, can. Learn about Roxicodone (Oxycodone Hydrochloride) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Estradiol Valerate Injection, USPESTRADIOL VALERATE - estradiol valerate injection Sandoz Inc- -- -- -- -- -Estradiol Valerate Injection, USPFor Intramuscular Use Only. ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCERClose clinical surveillance of all women taking estrogens is important. Adequate diagnostic measures, including endometrial sampling when indicated, should be undertaken to rule out malignancy in all cases of undiagnosed persistent or recurring abnormal vaginal bleeding. There is no evidence that the use of “natural” estrogens results in a different endometrial risk profile than synthetic estrogens at equivalent estrogen doses. It is unknown whether this finding applies to younger postmenopausal women or to women taking estrogen alone therapy. ![]() Dietary supplements have become a prominent part of American popular health culture, a fact attested to by the ready supply of supplements in pharmacies; chain stores. The United States Pharmacopeia and The National Formulary (USP–NF) is a book of public pharmacopeial standards for chemical and biological drug substances, dosage. Because of these risks, estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman. DESCRIPTIONEstradiol valerate injection, USP contains estradiol valerate, a long- acting estrogen in sterile oil solutions for intramuscular use. These solutions are clear, colorless to pale yellow. Formulations (per m. L): 1. 0 mg estradiol valerate in a vehicle containing 5 mg chlorobutanol (chloral derivative/preservative) and sesame oil; 2. Estradiol valerate is designated chemically as estra- 1,3,5(1. ![]() Although circulating estrogens exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human estrogen and is substantially more potent than its metabolites, estrone and estriol, at the receptor level. The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 7. After menopause, most endogenous estrogen is produced by conversion of and rostenedione, secreted by the adrenal cortex, to estrone by peripheral tissues. Thus, estrone and the sulfate conjugated form, estrone sulfate, are the most abundant circulating estrogens in postmenopausal women. Estrogens act through binding to nuclear receptors in estrogen- responsive tissues. To date, two estrogen receptors have been identified. These vary in proportion from tissue to tissue. Circulating estrogens modulate the pituitary secretion of the gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH), through a negative feedback mechanism. Estrogens act to reduce the elevated levels of these hormones seen in postmenopausal women. Pharmacokinetics. Absorption. Estrogens used in therapy are well absorbed through the skin, mucous membranes, and gastrointestinal tract. When applied for a local action, absorption is usually sufficient to cause systemic effects. When conjugated with aryl and alkyl groups for parenteral administration, the rate of absorption of oily preparations is slowed with a prolonged duration of action, such that a single intramuscular injection of estradiol valerate or estradiol cypionate is absorbed over several weeks. Distribution. The distribution of exogenous estrogens is similar to that of endogenous estrogens. Estrogens are widely distributed in the body and are generally found in higher concentrations in the sex hormone target organs. Estrogens circulate in the blood largely bound to sex hormone binding globulin (SHBG) and albumin. Metabolism. Exogenous estrogens are metabolized in the same manner as endogenous estrogens. Circulating estrogens exist in a dynamic equilibrium of metabolic interconversions. These transformations take place mainly in the liver. Estradiol is converted reversibly to estrone, and both can be converted to estriol, which is the major urinary metabolite. Estrogens also undergo enterohepatic recirculation via sulfate and glucuronide conjugation in the liver, biliary secretion of conjugates into the intestine, and hydrolysis in the gut followed by reabsorption. In postmenopausal women, a significant proportion of the circulating estrogens exist as sulfate conjugates, especially estrone sulfate, which serves as a circulating reservoir for the formation of more active estrogens. When given orally, naturally- occurring estrogens and their esters are extensively metabolized (first pass effect) and circulate primarily as estrone sulfate, with smaller amounts of other conjugated and unconjugated estrogenic species. This results in limited oral potency. By contrast, synthetic estrogens, such as ethinyl estradiol and the nonsteroidal estrogens, are degraded very slowly in the liver and other tissues, which results in their high intrinsic potency. Estrogen drug products administered by non- oral routes are not subject to first- pass metabolism, but also undergo significant hepatic uptake, metabolism, and enterohepatic recycling. Excretion. Estradiol, estrone, and estriol are excreted in the urine along with glucuronide and sulfate conjugates. Drug Interactions. In vitro and in vivo studies have shown that estrogens are metabolized partially by cytochrome P4. A4 (CYP3. A4). Therefore, inducers or inhibitors of CYP3. A4 may affect estrogen drug metabolism. Inducers of CYP3. A4 such as St. John’s Wort preparations (Hypericum perforatum), phenobarbital, carbamazepine, and rifampin may reduce plasma concentrations of estrogens, possibly resulting in a decrease in therapeutic effects and/or changes in the uterine bleeding profile. Inhibitors of CYP3. A4 such as erythromycin, clarithromycin, ketoconazole, itraconazole, ritonavir and grapefruit juice may increase plasma concentrations of estrogens and may result in side effects. Clinical Studies. Women’s Health Initiative Studies. The Women’s Health Initiative (WHI) enrolled a total of 2. CE) per day alone or the use of oral 0. MPA) per day compared to placebo in the prevention of certain chronic diseases. The primary endpoint was the incidence of coronary heart disease (CHD) (nonfatal myocardial infarction and CHD death), with invasive breast cancer as the primary adverse outcome studied. A “global index” included the earliest occurrence of CHD, invasive breast cancer, stroke, pulmonary embolism (PE), endometrial cancer, colorectal cancer, hip fracture, or death due to other cause. The study did not evaluate the effects of CE or CE/MPA on menopausal symptoms. The CE/MPA substudy was stopped early because, according to the predefined stopping rule, the increased risk of breast cancer and cardiovascular events exceeded the specified benefits included in the “global index”. Results of the CE/MPA substudy, which included 1. White, 6. 5% Black, 5. Hispanic), after an average follow- up of 5. Table 1 below. Table 1. Relative and Absolute Risk Seen in the CE/MPA Substudy of WHI. Event. The absolute excess risk of events included in the “global index” was 1. There was no difference between the groups in terms of all- cause mortality. The relative risk of probable dementia in the hormone therapy group was 2. CI, 1. 2. 1 to 3. Differences between groups became apparent in the first year of treatment. It is unknown whether these findings apply to younger postmenopausal women. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered. Treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure. Treatment of advanced androgen- dependent carcinoma of the prostate (for palliation only). CONTRAINDICATIONSEstradiol valerate injection, USP should not be used in women with any of the following conditions: Undiagnosed abnormal genital bleeding. Known, suspected, or history of cancer of the breast. Known or suspected estrogen- dependent neoplasia. Active deep vein thrombosis, pulmonary embolism or a history of these conditions. Active or recent (e. Liver dysfunction or disease. Estradiol Valerate Injection, USP should not be used in patients with known hypersensitivity to its ingredients. Known or suspected pregnancy. There is no indication for Estradiol Valerate Injection, USP in pregnancy. There appears to be little or no increased risk of birth defects in children born to women who have used estrogens and progestins from oral contraceptives inadvertently during early pregnancy. Should any of these occur or be suspected, estrogens should be discontinued immediately. Risk factors for arterial vascular disease (e. VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. Coronary Heart Disease and Stroke. In the Women’s Health Initiative (WHI) study, an increase in the number of myocardial infarctions and strokes has been observed in women receiving CE compared to placebo. These observations are preliminary. The increase in risk was observed in year one and persisted. In the same substudy of WHI, an increased risk of stroke was observed in women receiving CE/MPA compared to women receiving placebo (2. The increase in risk was observed after the first year and persisted. In postmenopausal women with documented heart disease (n=2,7. Heart and Estrogen/Progestin Replacement Study; HERS) treatment with CE/MPA (0. During an average follow- up of 4. CE/MPA did not reduce the overall rate of CHD events in postmenopausal women with established coronary heart disease. There were more CHD events in the CE/MPA- treated group than in the placebo group in year 1, but not during the subsequent years. Two thousand three hundred and twenty one women from the original HERS trial agreed to participate in an open label extension of HERS, HERS II. Average follow- up in HERS II was an additional 2. Rates of CHD events were comparable among women in the CE/MPA group and the placebo group in HERS, HERS II, and overall. Large doses of estrogen (5 mg conjugated estrogens per day), comparable to those used to treat cancer of the prostate and breast, have been shown in a large prospective clinical trial in men to increase the risks of nonfatal myocardial infarction, pulmonary embolism, and thrombophlebitis. Potassium Chloride in Dextrose and Sodium Chloride Injections USPPOTASSIUM CHLORIDE IN DEXTROSE AND SODIUM CHLORIDE - dextrose, sodium chloride and potassium chloride injection B. Braun Medical Inc.- -- -- -- -- -DESCRIPTION(See chart below for quantitative information.)Potassium Chloride in Dextrose and Sodium Chloride Injections USP are sterile, nonpyrogenic and contain no bacteriostatic or antimicrobial agents. These products are intended for intravenous administration. The formulas of the active ingredients are: Composition – Each 1. L contains: Solution Hydrous Dextrose USP Sodium Chloride USP Potassium Chloride USP Concentration of Electrolytes (m. Eq/liter) Calories perliter Calculated. Osmolaritym. Osmol/liter p. H Sodium Potassium Chloride Water for Injection USP qs 0. Potassium Chloride in 3. Dextrose and. 0. 3. Sodium Chloride Injection USP 3. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 5% Dextrose and. Sodium Chloride Injection USP 5 g 0. Potassium Chloride in 1. Dextrose and. 0. 2. Sodium Chloride Injection USP 1. The EXCEL Container is Latex- free, PVC- free, and DEHP- free. The plastic container is made from a multilayered film specifically developed for parenteral drugs. It contains no plasticizers and exhibits virtually no leachables. The solution contact layer is a rubberized copolymer of ethylene and propylene. The container is nontoxic and biologically inert. The container- solution unit is a closed system and is not dependent upon entry of external air during administration. The container is overwrapped to provide protection from the physical environment and to provide an additional moisture barrier when necessary. Addition of medication should be accomplished using complete aseptic technique. The closure system has two ports; the one for the administration set has a tamper evident plastic protector and the other is a medication addition site. Refer to the Directions for Use of the container. CLINICAL PHARMACOLOGYThese intravenous solutions provide electrolytes and calories, and are a source of water for hydration. They are capable of inducing diuresis depending on the clinical condition of the patient. Sodium, the major cation of the extracellular fluid, functions primarily in the control of water distribution, fluid balance, and osmotic pressure of body fluids. Sodium is also associated with chloride and bicarbonate in the regulation of the acid- base equilibrium of body fluid. Potassium, the principal cation of intracellular fluid, participates in carbohydrate utilization and protein synthesis, and is critical in the regulation of nerve conduction and muscle contraction, particularly in the heart. Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid- base balance of the body are reflected by changes in the chloride concentration. Dextrose provides a source of calories. Dextrose is readily metabolized, may decrease losses of body protein and nitrogen, promotes glycogen deposition and decreases or prevents ketosis if sufficient doses are provided. INDICATIONS AND USAGEThese intravenous solutions are indicated for use in adults and pediatric patients as sources of electrolytes, calories and water for hydration. CONTRAINDICATIONSThese solutions are contraindicated where the administration of sodium, potassium or chloride could be clinically detrimental. Solutions containing dextrose may be contraindicated in patients with hypersensitivity to corn products. WARNINGSThe administration of intravenous solutions can cause fluid and/or solute overload resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentration. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentration. Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency, and in clinical states in which there is sodium retention with edema. In patients with diminished renal function, administration of solutions containing sodium or potassium ions may result in sodium or potassium retention. Solutions containing potassium ions should be used with great care, if at all, in patients with hyperkalemia, severe renal failure, and in conditions in which potassium retention is present. PRECAUTIONSGeneral. These solutions should be used with care in patients with hypervolemia, renal insufficiency, urinary tract obstruction, or impending or frank cardiac decompensation. Extraordinary electrolyte losses such as may occur during protracted nasogastric suction, vomiting, diarrhea or gastrointestinal fistula drainage may necessitate additional electrolyte supplementation. Additional essential electrolytes, minerals and vitamins should be supplied as needed. Sodium- containing solutions should be administered with caution to patients receiving corticosteroids or corticotropin, or to other salt- retaining patients. Care should be exercised in administering solutions containing sodium or potassium to patients with renal or cardiovascular insufficiency, with or without congestive heart failure, particularly if they are postoperative or elderly. Potassium therapy should be guided primarily by serial electrocardiograms, especially in patients receiving digitalis. Serum potassium levels are not necessarily indicative of tissue potassium levels. Solutions containing potassium should be used with caution in the presence of cardiac disease, particularly when accompanied by renal disease. Solutions containing dextrose should be used with caution in patients with overt or known subclinical diabetes mellitus, or carbohydrate intolerance for any reason. To minimize the risk of possible incompatibilities arising from mixing any of these solutions with other additives that may be prescribed, the final infusate should be inspected for cloudiness or precipitation immediately after mixing, prior to administration, and periodically during administration. Do not use plastic container in series connection. If administration is controlled by a pumping device, care must be taken to discontinue pumping action before the container runs dry or air embolism may result. If administration is not controlled by a pumping device, refrain from applying excessive pressure (> 3. Hg) causing distortion to the container such as wringing or twisting. Such handling could result in breakage of the container. These solutions are intended for intravenous administration using sterile equipment. It is recommended that intravenous administration apparatus be replaced at least once every 2. Use only if solution is clear and container and seals are intact. Laboratory Tests. Clinical evaluation and periodic laboratory determinations are necessary to monitor changes in fluid balance, electrolyte concentrations, and acid- base balance during prolonged parenteral therapy or whenever the condition of the patient warrants such evaluation. Significant deviations from normal concentrations may require tailoring of the electrolyte pattern, in these or alternative solutions. Carcinogenesis, Mutagenesis, Impairment of Fertility. Studies with Potassium Chloride in Dextrose and Sodium Chloride Injections USP have not been performed to evaluate carcinogenic potential, mutagenic potential, or effects on fertility. Pregnancy. Teratogenic Effects. Pregnancy Category C. Animal reproduction studies have not been conducted with Potassium Chloride in Dextrose and Sodium Chloride Injections USP. It is also not known whether Potassium Chloride in Dextrose and Sodium Chloride Injections USP can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Potassium Chloride in Dextrose and Sodium Chloride Injections USP should be given to a pregnant woman only if clearly needed. Labor and Delivery. The effects of Potassium Chloride in Dextrose and Sodium Chloride Injections USP on the duration of labor or delivery, on the possibility that forceps delivery or other intervention or resuscitation of the newborn will be necessary, and on the later growth, development, and functional maturation of the child are unknown. As reported in the literature, potassium containing solutions have been administered during labor and delivery. Caution should be exercised, and the fluid balance, glucose and electrolyte concentrations, and acid- base balance, of both mother and fetus should be evaluated periodically or whenever warranted by the condition of the patient or fetus. Nursing Mothers. It is not known whether these drugs are excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Potassium Chloride in Dextrose and Sodium Chloride Injections USP are administered to a nursing woman. Pediatric Use. Safety and effectiveness of Potassium Chloride in Dextrose and Sodium Chloride Injections USP in pediatric patients have not been established by adequate and well- controlled studies. However, as referenced in the medical literature, potassium chloride injection has been used to treat pediatric patients with potassium deficiency when oral replacement therapy is not feasible. General Chapters: < 8. ANTIBIOTICS- MICROBIAL ASSAYSTo prepare assay plates using Petri dishes, place 2. 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The discovery shows that toxic substances of our own making have been around for a lot longer than we realized. By replicating a traditional method used to create water bottles and other items, a research team from the University of California, with the help of researchers from Stockholm University, has shown that native Californians inadvertently and unknowingly exposed themselves to dangerous chemicals known as polycyclic aromatic hydrocarbons (PAHs). These compounds, which has been linked to a wide range of health problems, are a noxious byproduct of warming bitumen, a petroleum- based substance that can be used as a sealant. The details of this discovery can now be found in the science journal Environmental Health. The California Channel Islands are unique in that they’re one of the few places in North America where archaeologists can find traces of continuous human occupation dating back to when the peopling of the Americas began, up until the Industrial Age. Extensive work on the islands has produced a rich and deep record of human occupation in the New World, including skeletal remains that date back over 1. Scientists have been able to trace signs of disease and stress in these skeletons over time, as populations grew in size, as their diets changed, and as societies evolved. But as the new research shows, certain declines in the health of these ancient people can likely be traced back to the introduction of bitumen- lined water bottles at least 5,0. In order to find out if the level of exposure was unsafe (according to modern dose limits established by the EPA), we had to replicate processes by which bitumen was used—in this case, the manufacture and use of bitumen- coated water bottles—and test the resulting PAH concentrations in the air, water, and food.”To that end, Sholts’ team engaged in a bit of experimental archaeology. Using the exact processes and tools used by the indigenous Californians, the researchers produced two different version of the ancient water bottles. The first was lined with soft bitumen known as “malak,” which is known to wash ashore after seeping up from the ocean floor, and the second bottle was lined with hard bitumen called “woqo,” which is found in oily land deposits. Following oral tradition, the researchers used stone tools and a bird bone awl to weave baskets from soft rush plants found in California. Abalone shells were used as mixing dish, and the bitumen was heated with metavolcanic pebbles before applying the substance to the basket by hand using the bone of a sea mammal. During the process, the researchers sampled the air using gas chromatography and mass spectrometry. They isolated, identified, and measured levels of PAHs, finding concentrations equal to or greater than those found in cigarette smoke. But while the fumes from the bitumen were at dangerous levels, the water stored in the in the bitumen- lined bottles did not contain toxic amounts. Consequently, Sholts says, the amounts of PAHs found in the water wouldn’t have been enough to induce health problems.“If someone regularly breathed fumes from melted bitumen—not just for making bottles, but possibly also for making boats, tools, objects for cooking/storing food, . Dermal exposure could have occurred when bitumen was applied directly to the body for ritual or medicinal purposes.” Sholts says that bitumen was readily available and a highly versatile substance for the people who lived on the Channel Islands, and that further research may provide more information about possible health effects. Importantly, this particular risk assessment was only focused on adult exposure. The researchers also learned through this experiment that the kind of bitumen that washes up on the Channel Islands (from subterranean seeps) was suitable for making these bottles. Previously, it was suggested that the quality was too poor, forcing people on the islands to be more dependent on bitumen from the terrestrial seeps on the mainland. In terms of next steps, Sholts’ team plans to continue to use experimental archaeology, toxicology, and other methods to better understand the health of indigenous Americans. A fascinating takeaway from this study is the realization that manufacturing techniques have been exposing people to toxins for thousands of years. Call it the dark side of ingenuity. Download the free trial version below to get started. Double-click the downloaded file to install the software. Flashcard Machine - create, study and share online flash cards A continuación le ofrecemos un resúmen ampliado, de algunos productos de equipamiento auxiliar analítico. 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Chess Notes. 10. 53. The BCMFrom Olimpiu G. Urcan (Singapore). Yates Kill Himself? It has been. lifted from Wikipedia. So more or less the only . InformationWeek.com: News, analysis and research for business technology professionals, plus peer-to-peer knowledge sharing. Engage with our community.The magazine identifies him as . A. brilliancy prize game. Eduardo Bauz. Layzell City of London Winter Tournament, 1. Queen. 1. 05. 15 gave some . Chernev put. . Early. Smyslov studies. Andrey Terekhov (Singapore) forwards a news item on. This report on a Kiev- Moscow schoolchildren. Our. correspondent asks whether 6. Cover of the first Japanese Naruto manga volume featuring Naruto Uzumaki. Online Order Support Request. For assistance with the installation, use, or uninstallation of your software, please visit Technical Support. Official online book store of the Chess Informant, publishing house established in 1966. Chess Informant ( Smyslov. 5. 92. 2 referred to the actor John Gilbert. Information about his possible interest in. His daughter Leatrice Gilbert Fountain wrote a. Dark Star (London, 1. ![]() Christmas Eve 1. 93. An. inscription by Botvinnik. From the title page of volume one of our set of Shakhmatnoe. Botvinnika (Moscow, 1. We take the recipient of Botvinnik. Blumberg. (C. N. s 1. Gerard Killoran (Ilkley, England) notes that Blumberg. New- York. Daily Tribune, 2. December 1. 90. 7: As regards Blumberg. We have a few others, including portraits of Steinitz. Lasker and Smyslov: 1. ![]() Emanuel. Lasker and hypnosis. From page 1. 43 of Combinations The Heart of Chess. Irving Chernev (New York, 1. Chernev included Georg Marco. According to pages 6. Samuel. Rosenthal. From Sean Robinson (Tacoma, WA, USA). It is not just a neglected. Under. different circumstances, it might have become Bobby. Teaches Chess II. As you noted in C. N. 7. 37. 5, Leslie Ault. Leslie Ault. Leslie. Ault, a US Intercollegiate champion, worked for. Basic Systems, Inc., the publisher and educational. Xerox. He gave an account of. The Genesis of Power Chess. Davenport, 1. 99. Unknown to. me, Stuart had a contract along with Donn. Mosenfelder (for writing) and Bobby Fischer (for the. After Donn was slowed down. I was asked to help him. I was given the job, nominally as. Our. job was to tidy up the text, make sure all analysis. Bobby Fischer in. At first he was suspicious and. The result, of course. Bobby Fischer Teaches Chess, which. Fischer. Originally, I. Fischer myself, but his. This I. was able to do, and the result was The Chess. Tutor: Elements of Combinations (1. The paperback printing was just at the end of. Fischer boom .. Although it is. Fischer, it may qualify. It included Fischer. It received very little attention. Also in 1. 97. 6, the same publisher brought out The. Chess Tutor: Opening Moves by Pierre R. Schwob and. George F. Opposite the title page, Walter Korn was. General Editor of the . In the United States, both books were published by. Mason/Charter, New York, and were advertised on page 3. June 1. 97. 6 Chess Life & Review: 1. The entry states that he was born in . A late. Lipsch. A Life in. Chess (Jefferson, 2. Stephen Davies gives a. April 1. 90. 3 as. The source of Marco. The comment about P- K4 was discussed on page. Chess Facts and Fables and in C. N. It was on page 1. Tarrasch. Alekhine has just played 2. Nf. 5- e. 3: 1. 05. Staunton. problems. John Townsend (Wokingham, England) writes. Qf. 5 hxg. 5 2 Qxf. Kh. 7 3 Qf. 5+. g. Re. 7+ Kh. 6 5 Qf. Kh. 5 6 Rh. 7+ Kg. Qf. 3 mate. Why did two very similar positions appear? If both. accounts are to be believed, and the two problems. No such match by Staunton at those odds. His contributions to C. N. A. . The Chess. Revolutionary by Jimmy Adams (Alkmaar, 2. The. title page of this 8. With translations from the Hungarian by Peter. Szab. He. explained that he just compiles the information and. He claimed it took him three days of work to put out. Serafino. Dubois. A particularly elegant recent book is Serafino. Dubois by Fabrizio Zavatarelli (Brescia, 2. A. deciphering task. Readers who enjoy a deciphering task may care to. Larger versions: Part one. Part two. The letter demonstrates that at least some of the. Capablanca. As shown in our feature. Hamburg. 1. 93. 0John Donaldson (Berkeley, CA, USA) has forwarded this. Larger. version. Credit: the World Chess Hall of Fame in St Louis, which. Isaac. Kashdan. Gangster. Chess. From the Falkirk Herald, 1. May 1. 93. 2. I was told an amusing story the. Capone. When the hold- ups and shootings. But what is even. Thus, it seems, pawns are. Can the original item. Pearson. As. R. Issued in Nizhny Novgorod and dated. An oddity is that the impressum page states that the. Another photograph of H. N. It is in the. recent two- volume reprint of the Womanhood. Rhoda A. Bowles) by Publishing House. Moravian Chess, but is a clear version available from. Breyer. and sources (C. N. 1. 05. 54)One of the many reasons why a book should give precise. That process is often very difficult with. Gyula Breyer. The Chess Revolutionary by Jimmy. Adams (Alkmaar, 2. From pages 1. 42- 1. The passage is. readily found in the Soltis book, whose index has only. Breyer, on page 1. A point of detail is that the words . Breyer v Tarrasch, Mannheim, 1. Page 3. 32 offers a typical example of how game. Jimmy Adams: These bald references are of little help. To mention. only the first one, Kagans Neueste Schachnachrichten. Breyer v Tarrasch game was played. The onus is thus. The. source of that piece specified on page 1. Full citations (exact. C. N. 5. 21. 5, and the. Breyer book thus takes a retrograde step by denying the. For instance, a small piece of. Breyer. The concluding pages. Such references are. Sometimes, out of the blue, a more rigorous approach to. Breyer. The text quoted by Adams is on pages 1. Breyer. book. On the substantive issue of the alleged . Evans on Chess. Richard Reti, who in 1. Incidentally, from the Breyer index (page 8. Evans is mentioned in. Evans Gambit. Pages 7. No date for the New York Times article is given. Adams, but there is a source at the bottom of page. A link, perhaps, to the on- line version of. Alekhine? A link, perhaps, to Alekhine on Carlsbad, 1. New. York Times, 1 August 1. A. reference, perhaps, to C. N. 1. 27. 4, which, over 3. Alekhine? No. Instead, astoundingly, the Adams book has this at the. Alekhine? If they. Quarterly. they will eventually find Alekhine. Such evident mistranscriptions have. Adams book, but why even consider. Quarterly for Chess History in the. A small example of what will inevitably go. Alekhine after he. Breyer and R. According to the Quarterly. Alekhine wrote. An article. Shakhmaty by the winner of the Moscow. E. D. Bogoljubow. Zukertort. 1. 05. Breyer book over 3. A few weeks. Fauber. Breyer. It is a mercy that few chess authors have written prose. R. E. From page 1. Impact. of Genius (Seattle, 1. Cameron, the winner of the. Mr J. Frank, to whom he had to. Each of the. players made 5. Singapore. Chess. The latest arrival is Singapore Chess. A History. 1. 94. Shashi Jayakumar and Olimpiu G. Urcan. (Singapore, 2. The book is available in hardback and paperback. The. Rookie. A paperback edition of The Rookie by Stephen. Moss has been published recently. A full page of quotes. Edward Lasker as . Mutchler in his chess. Society section of the Washington. Post, 1. 0 August 1. A. deciphering task (C. N. 1. 05. 57)The letter in C. N. 1. 05. 57 (see part one and part two) lay in a. Capablanca. The inscription was shown in C. N. 4. 47. 8. Although the closing signature in the letter to Hayden. Chess. Explorations) in connection with an earlier BCM. November 1. 93. 3, page 4. We have never found a copy of the 1. Jaque. Mate. B. H. Wood wrote about the Capablanca research of. Gilchrist and Hooper in the Illustrated London News. December 1. 96. 1, page 1. The final paragraph was an. The Quarterly. for Chess History. Unperturbed by criticism (in, for instance, C. N. Yates, taking the story. July 1. 90. 8 to May 1. The Quarterly. ends (pages 5. Fiala. Both. volumes were published by Mc. Farland, whose name is spelt. The second book, published nine. That feature takes up nearly 3. From page 4. 45: Despite the introductory word . It was not played by Aron Nimzowitsch. Zurich, or in 1. 90. The game, won by the master. As noted on page 5. Kings, Commoners and Knaves, it was published. Schachjahrbuch f. Theil. by Ludwig Bachmann: The imprint page of issue 1. Quarterly for. Chess History (printed in . It began 1 d. 4 f. Nc. 3 Nf. 6 4 Bg. Black. Annotating the. W. Henry. Sayen wrote regarding 5 f. This move is new, and. |
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